4lrr: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[4lrr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[4lrr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Eco57 Eco57]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LRR OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:024147825</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:024147825</ref><references group="xtra"/><references/> | ||
[[Category: | [[Category: Eco57]] | ||
[[Category: Thymidylate synthase]] | [[Category: Thymidylate synthase]] | ||
[[Category: Costi, M P.]] | [[Category: Costi, M P.]] | ||
Revision as of 12:20, 11 December 2013
Ternary complex between E. coli thymidylate synthase, dUMP, and F9
Template:ABSTRACT PUBMED 24147825
Function
[TYSY_ECO57] Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity).
About this Structure
4lrr is a 1 chain structure with sequence from Eco57. Full crystallographic information is available from OCA.
Reference
- Ferrari S, Calo S, Leone R, Luciani R, Costantino L, Sammak S, Di Pisa F, Pozzi C, Mangani S, Costi MP. 2'-deoxyuridine-5'-monophosphate substrate displacement in thymidylate synthase through 6-hydroxy-2H-naphtho[1,8-bc]furan-2-one derivatives. J Med Chem. 2013 Oct 22. PMID:24147825 doi:https://dx.doi.org/10.1021/jm4014086
