3wdd: Difference between revisions
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{{STRUCTURE_3wdd| PDB=3wdd | SCENE= }} | {{STRUCTURE_3wdd| PDB=3wdd | SCENE= }} | ||
===Mutant N-terminal domain of Mycobacterium tuberculosis ClpC1, F2Y, bound to Cyclomarin A=== | ===Mutant N-terminal domain of Mycobacterium tuberculosis ClpC1, F2Y, bound to Cyclomarin A=== | ||
{{ABSTRACT_PUBMED_24022489}} | |||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[3wdd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3wdd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884] and [http://en.wikipedia.org/wiki/Chainia_sp. Chainia sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WDD OCA]. | ||
[[Category: | ==Reference== | ||
<ref group="xtra">PMID:024022489</ref><references group="xtra"/><references/> | |||
[[Category: Chainia sp.]] | |||
[[Category: Noble, C G.]] | [[Category: Noble, C G.]] | ||
[[Category: Vasudevan, D.]] | [[Category: Vasudevan, D.]] | ||
[[Category: Chaperone]] | [[Category: Chaperone]] | ||
[[Category: Chaperone-antimicrobial protein complex]] | [[Category: Chaperone-antimicrobial protein complex]] | ||
Revision as of 12:32, 11 December 2013
Mutant N-terminal domain of Mycobacterium tuberculosis ClpC1, F2Y, bound to Cyclomarin A
Template:ABSTRACT PUBMED 24022489
Function
[CLPC1_MYCTU] ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity). Degrades anti-sigma-E factor RseA in the presence of ClpP2.
About this Structure
3wdd is a 2 chain structure with sequence from "bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884 and Chainia sp.. Full crystallographic information is available from OCA.
Reference
- Vasudevan D, Rao SP, Noble CG. Structural basis of mycobacterial inhibition by cyclomarin A. J Biol Chem. 2013 Oct 25;288(43):30883-91. doi: 10.1074/jbc.M113.493767. Epub, 2013 Sep 10. PMID:24022489 doi:https://dx.doi.org/10.1074/jbc.M113.493767
