3epk: Difference between revisions
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{{STRUCTURE_3epk| PDB=3epk | SCENE= }} | {{STRUCTURE_3epk| PDB=3epk | SCENE= }} | ||
===CRYSTALLOGRAPHIC SNAPSHOTS OF EUKARYOTIC DIMETHYLALLYLTRANSFERASE ACTING ON TRNA: INSIGHT INTO TRNA RECOGNITION AND REACTION MECHANISM=== | |||
{{ABSTRACT_PUBMED_18852462}} | |||
=== | ==Function== | ||
[[http://www.uniprot.org/uniprot/MOD5_YEAST MOD5_YEAST]] Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in the anticodon loop on a specific subset of tRNAs both in the cytosol and the mitochondrion, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A). This modification optimizes the codon:anticodon fit in the ribosome and promotes translational fidelity. Competes with the farnesyl pyrophosphate synthase ERG20 for the common substrate dimethylallyl diphosphate (DMAPP).<ref>PMID:3031456</ref> <ref>PMID:10618371</ref> <ref>PMID:21873461</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3epk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3epk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EPK OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:018852462</ref><references group="xtra"/> | <ref group="xtra">PMID:018852462</ref><references group="xtra"/><references/> | ||
[[Category: | [[Category: Atcc 18824]] | ||
[[Category: TRNA dimethylallyltransferase]] | [[Category: TRNA dimethylallyltransferase]] | ||
[[Category: Huang, R H.]] | [[Category: Huang, R H.]] | ||
