2rgf: Difference between revisions

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==Overview==

The solution structure of the Ras-binding domain (RBD) of Ral, guanine-nucleotide exchange factor RalGEF was solved by NMR spectroscopy., The overall structure is similar to that of Raf-RBD, another effector of, Ras, although the sequence identity is only 13%. 15N chemical shifts, changes in the complex of RalGEF-RBD with Ras indicate an interaction, similar to the intermolecular beta-sheet observed for the complex between, Ras and Raf-RBD.

The solution structure of the Ras-binding domain (RBD) of Ral guanine-nucleotide exchange factor RalGEF was solved by NMR spectroscopy. The overall structure is similar to that of Raf-RBD, another effector of Ras, although the sequence identity is only 13%. 15N chemical shifts changes in the complex of RalGEF-RBD with Ras indicate an interaction similar to the intermolecular beta-sheet observed for the complex between Ras and Raf-RBD.

==About this Structure==

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[[Category: Geyer, M.]]

[[Category: Herrmann, C.]]

[[Category: Kalbitzer, H.R.]]

[[Category: Kalbitzer, H R.]]

[[Category: Wittinghofer, A.]]

[[Category: ralgds]]

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[[Category: rbd]]

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@@ Line 4: / Line 4: @@
 ==Overview==
-The solution structure of the Ras-binding domain (RBD) of Ral, guanine-nucleotide exchange factor RalGEF was solved by NMR spectroscopy., The overall structure is similar to that of Raf-RBD, another effector of, Ras, although the sequence identity is only 13%. 15N chemical shifts, changes in the complex of RalGEF-RBD with Ras indicate an interaction, similar to the intermolecular beta-sheet observed for the complex between, Ras and Raf-RBD.
+The solution structure of the Ras-binding domain (RBD) of Ral guanine-nucleotide exchange factor RalGEF was solved by NMR spectroscopy. The overall structure is similar to that of Raf-RBD, another effector of Ras, although the sequence identity is only 13%. 15N chemical shifts changes in the complex of RalGEF-RBD with Ras indicate an interaction similar to the intermolecular beta-sheet observed for the complex between Ras and Raf-RBD.
 ==About this Structure==
@@ Line 15: / Line 15: @@
 [[Category: Geyer, M.]]
 [[Category: Herrmann, C.]]
-[[Category: Kalbitzer, H.R.]]
+[[Category: Kalbitzer, H R.]]
 [[Category: Wittinghofer, A.]]
 [[Category: ralgds]]
@@ Line 23: / Line 23: @@
 [[Category: rbd]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Feb 15 17:42:07 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:47:06 2008''