4mih: Difference between revisions

Line 1:

~~'''Unreleased~~ structure~~'''~~

===Pyranose 2-oxidase from Phanerochaete chrysosporium, recombinant H158A mutant===

The ~~entry 4mih~~ is ~~ON HOLD~~ ~~until Paper Publication~~

==Function==

[[http://www.uniprot.org/uniprot/P2OX_PHACH P2OX_PHACH]] Catalyzes the oxidation of various aldopyranoses and disaccharides on carbon-2 to the corresponding 2-keto sugars concomitant with the reduction of O(2) to H(2)O(2). Plays an important role in lignin degradation of wood rot fungi by supplying the essential cosubstrate H(2)O(2) for the ligninolytic peroxidases, lignin peroxidase and manganese-dependent peroxidase. The preferred substrate is D-glucose which is converted to 2-dehydro-D-glucose, an intermediate of a secondary metabolic pathway leading to the antibiotic cortalcerone. Acts also on D-xylose, together with D-glucose the major sugars derived from wood, on L-sorbose, D-galactose and 1,5-anhydroglucitol, a diagnostic marker of diabetes mellitus.<ref>PMID:9210340</ref> <ref>PMID:8661938</ref>

~~Authors~~: ~~Hassan, N., Tan, T.C., Spadiut, O., Pisanelli, I., Fusco, L~~.~~, Haltrich, D~~.~~, Peterbauer, C~~.~~, Divne, C~~.

==About this Structure==

[[4mih]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MIH OCA].

~~Description~~: Pyranose 2-~~oxidase from Phanerochaete chrysosporium, recombinant H158A mutant~~

==Reference==

[[Category: Pyranose oxidase]]

[[Category: Divne, C.]]

[[Category: Fusco, L.]]

[[Category: Haltrich, D.]]

[[Category: Hassan, N.]]

[[Category: Peterbauer, C.]]

[[Category: Pisanelli, I.]]

[[Category: Spadiut, O.]]

[[Category: Tan, T C.]]

[[Category: Flavinylation]]

[[Category: Gmc oxidoreductase]]

[[Category: Homotetramer]]

[[Category: Hyphae]]

[[Category: Oxidoreductase]]

[[Category: Phbh fold]]

[[Category: Pyranose 2-oxidaser oxidoreductase]]

[[Category: Rossmann fold]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{Large structure}}
+{{STRUCTURE_4mih|  PDB=4mih  |  SCENE=  }}
+===Pyranose 2-oxidase from Phanerochaete chrysosporium, recombinant H158A mutant===
+{{ABSTRACT_PUBMED_24282677}}
-The entry 4mih is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/P2OX_PHACH P2OX_PHACH]] Catalyzes the oxidation of various aldopyranoses and disaccharides on carbon-2 to the corresponding 2-keto sugars concomitant with the reduction of O(2) to H(2)O(2). Plays an important role in lignin degradation of wood rot fungi by supplying the essential cosubstrate H(2)O(2) for the ligninolytic peroxidases, lignin peroxidase and manganese-dependent peroxidase. The preferred substrate is D-glucose which is converted to 2-dehydro-D-glucose, an intermediate of a secondary metabolic pathway leading to the antibiotic cortalcerone. Acts also on D-xylose, together with D-glucose the major sugars derived from wood, on L-sorbose, D-galactose and 1,5-anhydroglucitol, a diagnostic marker of diabetes mellitus.<ref>PMID:9210340</ref> <ref>PMID:8661938</ref>
-Authors: Hassan, N., Tan, T.C., Spadiut, O., Pisanelli, I., Fusco, L., Haltrich, D., Peterbauer, C., Divne, C.
+==About this Structure==
+[[4mih]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MIH OCA].
-Description: Pyranose 2-oxidase from Phanerochaete chrysosporium, recombinant H158A mutant
+==Reference==
+<ref group="xtra">PMID:024282677</ref><references group="xtra"/><references/>
+[[Category: Pyranose oxidase]]
+[[Category: Divne, C.]]
+[[Category: Fusco, L.]]
+[[Category: Haltrich, D.]]
+[[Category: Hassan, N.]]
+[[Category: Peterbauer, C.]]
+[[Category: Pisanelli, I.]]
+[[Category: Spadiut, O.]]
+[[Category: Tan, T C.]]
+[[Category: Flavinylation]]
+[[Category: Gmc oxidoreductase]]
+[[Category: Homotetramer]]
+[[Category: Hyphae]]
+[[Category: Oxidoreductase]]
+[[Category: Phbh fold]]
+[[Category: Pyranose 2-oxidaser oxidoreductase]]
+[[Category: Rossmann fold]]