2lu9: Difference between revisions
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{{STRUCTURE_2lu9| PDB=2lu9 | SCENE= }} | |||
===NMR solution structure of recombinant Tamapin=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/KAX54_MESTA KAX54_MESTA]] Blocks small conductance calcium-activated potassium channels in pyramidal neurons of the hippocampus. Displays a unique, remarkable selectivity for SK2/KCNN2 versus SK1/KCNN1 and SK3/KCNN3 channels.<ref>PMID:12239213</ref> | |||
==About this Structure== | |||
[[2lu9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LU9 OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Ramirez-Cordero, B.]] | |||
[[Category: Rio-Portilla, F del.]] | |||
[[Category: Cs alpha beta]] | |||
[[Category: Toxin]] | |||
Revision as of 13:42, 11 December 2013
NMR solution structure of recombinant Tamapin
Function
[KAX54_MESTA] Blocks small conductance calcium-activated potassium channels in pyramidal neurons of the hippocampus. Displays a unique, remarkable selectivity for SK2/KCNN2 versus SK1/KCNN1 and SK3/KCNN3 channels.[1]
About this Structure
2lu9 is a 1 chain structure. Full experimental information is available from OCA.
Reference
- ↑ Pedarzani P, D'hoedt D, Doorty KB, Wadsworth JD, Joseph JS, Jeyaseelan K, Kini RM, Gadre SV, Sapatnekar SM, Stocker M, Strong PN. Tamapin, a venom peptide from the Indian red scorpion (Mesobuthus tamulus) that targets small conductance Ca2+-activated K+ channels and afterhyperpolarization currents in central neurons. J Biol Chem. 2002 Nov 29;277(48):46101-9. Epub 2002 Sep 17. PMID:12239213 doi:https://dx.doi.org/10.1074/jbc.M206465200
