4lkd: Difference between revisions
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{{STRUCTURE_4lkd| PDB=4lkd | SCENE= }} | |||
===Crystal Structure of Pseudomonas aeruginosa Lectin LecA Complexed with GalA-QRS at 2.31 A Resolution=== | |||
{{ABSTRACT_PUBMED_24307364}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PA1L_PSEAE PA1L_PSEAE]] D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity. | |||
==About this Structure== | |||
[[4lkd]] is a 16 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LKD OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024307364</ref><references group="xtra"/><references/> | |||
[[Category: Kadam, R U.]] | |||
[[Category: Reymond, J L.]] | |||
[[Category: Stocker, A.]] | |||
[[Category: Galactose]] | |||
[[Category: Lectin fold]] | |||
[[Category: Sugar binding protein]] | |||
[[Category: Sugar binding protein-inhibitor complex]] | |||
Revision as of 10:25, 18 December 2013
Crystal Structure of Pseudomonas aeruginosa Lectin LecA Complexed with GalA-QRS at 2.31 A Resolution
Template:ABSTRACT PUBMED 24307364
Function
[PA1L_PSEAE] D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity.
About this Structure
4lkd is a 16 chain structure. Full crystallographic information is available from OCA.
Reference
- Kadam RU, Bergmann M, Garg D, Gabrieli G, Stocker A, Darbre T, Reymond JL. Structure-Based Optimization of the Terminal Tripeptide in Glycopeptide Dendrimer Inhibitors of Pseudomonas aeruginosa Biofilms Targeting LecA. Chemistry. 2013 Dec 9;19(50):17054-63. doi: 10.1002/chem.201302587. Epub 2013 Nov, 4. PMID:24307364 doi:https://dx.doi.org/10.1002/chem.201302587
