Interleukin-1 beta: Difference between revisions

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[http://en.wikipedia.org/wiki/Interleukin-1_receptor Interleukin-1 receptor] complex with ligand and go through the plasma membrane.   
[http://en.wikipedia.org/wiki/Interleukin-1_receptor Interleukin-1 receptor] complex with ligand and go through the plasma membrane.   
<scene name='57/571319/Scene_2/2'> Type 1 Interleukin-1 receptor complex with Interleukin-1 beta</scene> 3D structure is showing here. Ribbon diagram of s-IL 1R complex to IL-1β. The <scene name='57/571319/Scene_2/3'>complex</scene> has approximate dimensions of 97Å×52 Å ×35 Å with one s-IL1R molecule wrapping around the IL-1β molecule with 1:1 ratio. Quoted here[5]: Domain 3 provides a 'lid' which covers most of the top of the IL-1β  β-barrel, whereas domains 1 and 2 from a groove which binds to the lower rim of the barrel. Here,Domains 1,2 and 3 of s-IL 1R are colored light, medium and dark blue, respectively. IL-1β is yellow, with site A residues in green and site B residues in red.The structure is oriented so that the carboxy terminus of s-IL 1R and the cell membrane are at the bottom of the picture.
<scene name='57/571319/Scene_2/2'> Type 1 Interleukin-1 receptor complex with Interleukin-1 beta</scene> 3D structure is showing here. Ribbon diagram of s-IL 1R complex to IL-1β. The complex has approximate dimensions of 97Å×52 Å ×35 Å with one s-IL1R molecule wrapping around the IL-1β molecule with 1:1 ratio. In the <scene name='57/571319/Scene_2/3'>complex</scene>, domain 3 provides a 'lid' which covers most of the top of the IL-1β  β-barrel, whereas domains 1 and 2 from a groove which binds to the lower rim of the barrel[5]. Here,Domains 1,2 and 3 of s-IL 1R are colored light, medium and dark blue, respectively. IL-1β is yellow, with site A residues in green and site B residues in red.The structure is oriented so that the carboxy terminus of s-IL 1R and the cell membrane are at the bottom of the picture.