Sandbox Reserved 821: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 5: | Line 5: | ||
= Human C-reactive protein (CRP) = | = Human C-reactive protein (CRP) = | ||
The C-reactive protein (CRP) is a plasma protein, mainly synthesized by the liver. | The C-reactive protein (CRP) is a plasma protein, mainly synthesized by the liver. Its concentration may increase rapidly, | ||
as much as 1000-fold or more, in response to tissue injury, infection and inflammation: It's an acute-phase protein. | |||
This important rise in amount after inflammatory stimulus suggests that CRP is a part of the innate immune response in the host defense. | |||
CRP is a pattern recognition molecule, binding to specific molecular configurations that are typically exposed during cell death or found on the surfaces of pathogens. | |||
== '''Structure of CRP''' == | == '''Structure of CRP''' == | ||
