Sandbox Reserved 828: Difference between revisions
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<Structure load='1ab4' size='400' frame='true' align='right' caption=' | <Structure load='1ab4' size='400' frame='true' align='right' caption='Monomer of GyrA59 subunit at 2.8Å (1ab4.pdb)' scene='56/568026/Coloured/1'> | ||
[[Image:1ab4.png|left|200px]] | [[Image:1ab4.png|left|200px]] | ||
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The gyrase structure reveals a '''new cluster of conserved residues''', juxtaposing Tyr 122 and Arg 121 from one monomer and His 80, Arg 32 and Lys 42 from the other monomer. '''This cluster may form the active site of the breakage–reunion reaction''', with the other conserved positive charges (Arg 46 and Arg 47) anchoring the non-covalently bound 3' end of the cleaved DNA. | The gyrase structure reveals a '''new cluster of conserved residues''', juxtaposing Tyr 122 and Arg 121 from one monomer and His 80, Arg 32 and Lys 42 from the other monomer. '''This cluster may form the active site of the breakage–reunion reaction''', with the other conserved positive charges (Arg 46 and Arg 47) anchoring the non-covalently bound 3' end of the cleaved DNA. | ||
<Structure load='1ab4_mm1.pdb' size='300' frame='true' align='right' caption=' | <Structure load='1ab4_mm1.pdb' size='300' frame='true' align='right' caption='GyrA59, Breakage/Reunion subunit (dimer)' scene='56/568026/Biounit/1' /> | ||
