Sandbox Reserved 821: Difference between revisions
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== '''Structure of CRP''' == | == '''Structure of CRP''' == | ||
CRP is a pentamer: it contains five identical �23-kDa protomers, noncovalently associated (van der Waals contacts or hydrogen bonding) around a central pore. All members of the “pentraxins” family have this general structure. | |||
Each protomer has a recognition face (also called B face) with a phosphocholine binding site, made of a two-layered β sheet. The other face - the effector face (or A face) - where complement C1q and Fc� receptors bind. | |||
== '''The Calcium and Phosphocholine binding sites''' == | == '''The Calcium and Phosphocholine binding sites''' == | ||
