3pvc: Difference between revisions
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{{STRUCTURE_3pvc| PDB=3pvc | SCENE= }} | {{STRUCTURE_3pvc| PDB=3pvc | SCENE= }} | ||
===Crystal structure of apo MnmC from Yersinia Pestis=== | ===Crystal structure of apo MnmC from Yersinia Pestis=== | ||
{{ABSTRACT_PUBMED_23617613}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/MNMC_YERPE MNMC_YERPE]] Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity). | |||
==About this Structure== | ==About this Structure== | ||
[[3pvc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3pvc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pestis"_(lehmann_and_neumann_1896)_migula_1900 "bacillus pestis" (lehmann and neumann 1896) migula 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PVC OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:023617613</ref><references group="xtra"/><references/> | |||
[[Category: Almo, S C.]] | [[Category: Almo, S C.]] | ||
[[Category: Kim, J.]] | [[Category: Kim, J.]] | ||
Revision as of 08:26, 25 December 2013
Crystal structure of apo MnmC from Yersinia Pestis
Template:ABSTRACT PUBMED 23617613
Function
[MNMC_YERPE] Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity).
About this Structure
3pvc is a 1 chain structure with sequence from "bacillus_pestis"_(lehmann_and_neumann_1896)_migula_1900 "bacillus pestis" (lehmann and neumann 1896) migula 1900. Full crystallographic information is available from OCA.
Reference
- Kim J, Almo SC. Structural basis for hypermodification of the wobble uridine in tRNA by bifunctional enzyme MnmC. BMC Struct Biol. 2013 Apr 24;13:5. doi: 10.1186/1472-6807-13-5. PMID:23617613 doi:10.1186/1472-6807-13-5
