4h80: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4h80|  PDB=4h80  |  SCENE=  }}
===Crystal structure of human ALDH3A1 with its isozyme selective inhibitor - N-[4-(4-methylsulfonyl-2-nitroanilino)phenyl]acetamide===


The entry 4h80 is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/AL3A1_HUMAN AL3A1_HUMAN]] ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.


Authors: Hurley, T.D., Parajuli, B.
==About this Structure==
 
[[4h80]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H80 OCA].
Description: Crystal structure of human ALDH3A1 with its isozyme selective inhibitor -N-[4-(4-methylsulfonyl-2-nitroanilino)phenyl]acetamide
[[Category: Hurley, T D.]]
[[Category: Parajuli, B.]]
[[Category: Catalyzes benzaldehyde]]
[[Category: Dehydrogenase]]
[[Category: Nadp+ binding]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
[[Category: Rossman fold]]