4guk: Difference between revisions
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{{STRUCTURE_4guk| PDB=4guk | SCENE= }} | |||
===New crystal form structure of human NCS1=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/NCS1_HUMAN NCS1_HUMAN]] Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel (By similarity). | |||
==About this Structure== | |||
[[4guk]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GUK OCA]. | |||
[[Category: F., Chengpeng.]] | |||
[[Category: L., Elias.]] | |||
[[Category: Alpha]] | |||
[[Category: Neuronal calcium sensor]] | |||
[[Category: Protein binding]] | |||
Revision as of 10:24, 25 December 2013
New crystal form structure of human NCS1
Function
[NCS1_HUMAN] Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel (By similarity).
About this Structure
4guk is a 4 chain structure. Full crystallographic information is available from OCA.
