4njp: Difference between revisions
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{{STRUCTURE_4njp| PDB=4njp | SCENE= }} | |||
===Proteolysis inside the membrane is a rate-governed reaction not Driven by substrate affinity=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/GLPG_ECOLI GLPG_ECOLI]] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.<ref>PMID:17099694</ref> <ref>PMID:16216077</ref> | |||
==About this Structure== | |||
[[4njp]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NJP OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Rhomboid protease]] | |||
[[Category: Baker, R P.]] | |||
[[Category: Cho, S.]] | |||
[[Category: Dickey, S W.]] | |||
[[Category: Urban, S.]] | |||
[[Category: Hydrolase-membrane protein complex]] | |||
[[Category: Intramembrane protease]] | |||
[[Category: Rhomboid protease]] | |||
Revision as of 10:29, 25 December 2013
Proteolysis inside the membrane is a rate-governed reaction not Driven by substrate affinity
Function
[GLPG_ECOLI] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.[1] [2]
About this Structure
4njp is a 1 chain structure. Full crystallographic information is available from OCA.
Reference
- ↑ Wu Z, Yan N, Feng L, Oberstein A, Yan H, Baker RP, Gu L, Jeffrey PD, Urban S, Shi Y. Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry. Nat Struct Mol Biol. 2006 Dec;13(12):1084-91. Epub 2006 Nov 10. PMID:17099694 doi:10.1038/nsmb1179
- ↑ Maegawa S, Ito K, Akiyama Y. Proteolytic action of GlpG, a rhomboid protease in the Escherichia coli cytoplasmic membrane. Biochemistry. 2005 Oct 18;44(41):13543-52. PMID:16216077 doi:10.1021/bi051363k
