Sandbox Reserved 828: Difference between revisions

Revision as of 14:00, 26 December 2013 view source Pierre Ortalo (talk \| contribs) 80 edits No edit summary ← Older edit		Revision as of 14:17, 26 December 2013 view source Pierre Ortalo (talk \| contribs) 80 edits No edit summary Newer edit →
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	'''The A protein''' breaks and religates DNA as the DNA cleavage core and the CTD lies on it.		'''The A protein''' breaks and religates DNA as the DNA cleavage core and the CTD lies on it.
	The gyrA 59kDa N-ter domain is called Breakage and reunion domain. It is composed of two domains at the <scene name='56/568026/Head/2'>head</scene> region : a winged-helix-turn-helix domain or winged helix domain (WHD) where lies the catalytic tyrosines and a tower domain with alpha/beta structure that participates in DNA bending during cleavage.		The gyrA 59kDa N-ter domain is called Breakage and reunion domain. It is composed of two domains at the <scene name='56/568026/Head/2'>head</scene> region : a winged-helix-turn-helix domain or winged helix domain (WHD) where lies the catalytic tyrosines and a tower domain with alpha/beta structure that participates in DNA bending during cleavage. The ‘head’ dimer interface is dominated by an antiparallel side by-side packing of the alpha3 helices (the first helix of the HTH motif) from each monomer, together with their adjoining loops.At the top of the interface, the ‘recognition’ helices (alpha4) make a head-to-head antiparallel dimer contact.

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