Sandbox Reserved 828: Difference between revisions
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a winged-helix-turn-helix domain or <scene name='56/568026/Whd/1'>winged helix domain (WHD</scene>) where lies the catalytic tyrosines: the active-site tyrosines <scene name='56/568026/Tyr122/1'>(Tyr 122)</scene> are on loops at either end of the dimer interface. | a winged-helix-turn-helix domain or <scene name='56/568026/Whd/1'>winged helix domain (WHD</scene>) where lies the catalytic tyrosines: the active-site tyrosines <scene name='56/568026/Tyr122/1'>(Tyr 122)</scene> are on loops at either end of the dimer interface. | ||
a tower domain with alpha/beta structure that participates in DNA bending during cleavage. | a <scene name='56/568026/Tower/1'>tower domain</scene> with alpha/beta structure that participates in DNA bending during cleavage. | ||
The ‘head’ dimer interface is dominated by an antiparallel side by-side packing of the <scene name='56/568026/Alpha3/2'>alpha 3</scene> (the first helix of the HTH motif) from each monomer, together with their adjoining loops. At the top of the interface, the ‘recognition’ helices <scene name='56/568026/Alpha4/1'>alpha4</scene> make a head-to-head antiparallel dimer contact. | The ‘head’ dimer interface is dominated by an antiparallel side by-side packing of the <scene name='56/568026/Alpha3/2'>alpha 3</scene> (the first helix of the HTH motif) from each monomer, together with their adjoining loops. At the top of the interface, the ‘recognition’ helices <scene name='56/568026/Alpha4/1'>alpha4</scene> make a head-to-head antiparallel dimer contact. | ||
