Sandbox Reserved 829: Difference between revisions

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	Nuclear translocation of transcription factors is a crucial requirement for their action and stimulus-dependent nuclear translocation can serve as a mechanism to regulate gene expression at the level of transcription initiation.		Nuclear translocation of transcription factors is a crucial requirement for their action and stimulus-dependent nuclear translocation can serve as a mechanism to regulate gene expression at the level of transcription initiation.
	NLS is composed of several basic amino acids such as arginine (R) and lysine (K), as we can see in the NLS sequence RRMKWKK of PDX-1. This motif is sufficient for the nuclear import of PDX-1.<ref>PMID : 10567702</ref>		NLS is composed of several basic amino acids such as arginine (R) and lysine (K), as we can see in the NLS sequence RRMKWKK (basic amino acids) of PDX-1. This motif is sufficient for the nuclear import of PDX-1.<ref>PMID : 10567702</ref>

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