Sandbox Reserved 829: Difference between revisions
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Megane Denu (talk | contribs) No edit summary |
Megane Denu (talk | contribs) No edit summary |
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Morover, it is important to note that PDX-1 is located in the nucleus of cells. | Morover, it is important to note that PDX-1 is located in the nucleus of cells. | ||
[[Image:Schematic representation of functional domains and phosphorylation sites of PDX-1.jpg|right|580px|thumb|Schematic representation of functional domains and phosphorylation sites of PDX-1]] | |||
PDX-1 contains, at the N-terminus, a transactivation domain ( from 1 to 79 amino acids) and the middle region of the protein is composed of a homeodomain (from 146 to 206 amino acids) which is essential for DNA binding and protein-protein interactions. | PDX-1 contains, at the N-terminus, a transactivation domain ( from 1 to 79 amino acids) and the middle region of the protein is composed of a homeodomain (from 146 to 206 amino acids) which is essential for DNA binding and protein-protein interactions. | ||
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http://atlasgeneticsoncology.org/Genes/PDX1ID43921ch13q12.html | http://atlasgeneticsoncology.org/Genes/PDX1ID43921ch13q12.html | ||
(tres descriptif) | (tres descriptif) | ||
http://ghr.nlm.nih.gov/gene/PDX1 (gene sur chromosome 13q12.1) | |||
http://diabetes.diabetesjournals.org/content/51/suppl_3/S320.long | http://diabetes.diabetesjournals.org/content/51/suppl_3/S320.long | ||
