Sandbox Reserved 820: Difference between revisions
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'''Calsequestrin-2''' (or '''CASQ2''') is the soluble Ca<sup>2+</sup> binding protein in the sarcoplasmic reticulum lumen of the cardiac muscle cells. CASQ2 could be either in a monomeric, homodimeric, or homooligomeric chain form depending on its bounds with Ca<sup>2+</sup>. Mutations of CASQ2 are involved in cardiac diseases such as Catecholaminergic Polymorphic Ventricular Tachycardia. | '''Calsequestrin-2''' (or '''CASQ2''') is the soluble Ca<sup>2+</sup> binding protein in the sarcoplasmic reticulum lumen of the cardiac muscle cells. CASQ2 could be either in a monomeric, homodimeric, or homooligomeric chain form depending on its bounds with Ca<sup>2+</sup>. Mutations of CASQ2 are involved in cardiac diseases such as Catecholaminergic Polymorphic Ventricular Tachycardia. | ||
[[Image:LoadBinary 004.gif| | [[Image:LoadBinary 004.gif|350px|left|thumb|Calsequestrin in the calcium cycle of myocyte contraction]] | ||
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== Biological role == | == Biological role == | ||
