Sandbox Reserved 813

This Sandbox is Reserved from 06/12/2018, through 30/06/2019 for use in the course "Structural Biology" taught by Bruno Kieffer at the University of Strasbourg, ESBS. This reservation includes Sandbox Reserved 1480 through Sandbox Reserved 1543.

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Introduction

The POU family come from the acronym of three transcription factors : Pit-1, Oct-1 and Oct-2 and Unc-86.

Oct-4 structure

There are two diffent domains in the Oct-4 sequence : the Pou-specific domain (POUs) located on the N-terminal subunit and the homeodomain located in the C-terminal subunit of the sequence.

Pou-specific domain

The Pou-specific domain is located on the N-terminal site of the Oct-4 sequence and precisely from the 131th amino acid to the 205th. The POU-specific domain

Homeodomain

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