Sandbox Reserved 828: Difference between revisions
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* Unknotting DNA strands | * Unknotting DNA strands | ||
Contrary to the introduction of negative supercoils, some of these reactions don't necessarily need the energy from ATP-hydrolysis. | Contrary to the introduction of negative supercoils, '''some of these reactions don't necessarily need the energy from ATP-hydrolysis.''' | ||
The cleavage of DNA is achieved by a '''transesterification reaction between the tyrosines <scene name='56/568026/Tyr122/1'>(Tyr 122)</scene> and the target phosphoryl groups on opposing strands of the DNA backbone''', resulting in the tyrosine being covalentlty attached to the 5' end of the cleaved segment with a 4-base overhang. | The cleavage of DNA is achieved by a '''transesterification reaction between the tyrosines <scene name='56/568026/Tyr122/1'>(Tyr 122)</scene> and the target phosphoryl groups on opposing strands of the DNA backbone''', resulting in the tyrosine being covalentlty attached to the 5' end of the cleaved segment with a 4-base overhang. | ||
