Sandbox Reserved 829: Difference between revisions

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Majors differences between conformations A and B  are in the major groove. Three phosphate contacts are specific to conformation A: Asn 51 with Ade 2, and Arg 31 and Lys 46 with Ade 8*. However, conformation B is more specific than conformation A.  
Majors differences between conformations A and B  are in the major groove. Three phosphate contacts are specific to conformation A: Asn 51 with Ade 2, and Arg 31 and Lys 46 with Ade 8*. However, conformation B is more specific than conformation A.  


Actually, in conformation B, Gln 50 formes a water-mediated contact with Gua 5 and Thy 6* , and Asn 51 binds Ade 2 in addition to Ade 3.  
Actually, in conformation B, Gln 50 formes a water-mediated contact with Gua 5 and Thy 6* , and <scene name='56/568027/Asn51/1'>Asn 51</scene> binds Ade 2 in addition to Ade 3.