Sandbox Reserved 825: Difference between revisions

Line 44:

group of phosphatidic acid.

[[Image:FRB Phosphatidic Acid.png|upright=1.25|~~left~~|thumb| Fig.2 A representative view of phosphatidic acid docked into its binding site on the FRB domain.]]

[[Image:FRB Phosphatidic Acid.png|upright=1.25|center|thumb| Fig.2 A representative view of phosphatidic acid docked into its binding site on the FRB domain.]]

Other molecules like the novel class inhibitor '''HTS-1''' (4-[6-{[(1S,2R)-2-(benzyloxy)cyclopentyl]acety}-4-(2-thienyl)pyridin-2-yl]-4-xobutanoic acid)

Line 51:

binding. <ref> PMID: 17684489 </ref>

[[Image:FRB HTS-1 Rapamycin.png|~~left~~|upright=2| thumb| Fig.3 A representative view of the mTOR inhibitor HTS-1 docked into its binding site on the FRB domain on the left. On the right, the location and conformation of rapamycin bound to the FRB domain in the ternary complex formed with FKBP12 is illustrated, with the domain shown in the same orientation as on the left.]]

[[Image:FRB HTS-1 Rapamycin.png|center|upright=2| thumb| Fig.3 A representative view of the mTOR inhibitor HTS-1 docked into its binding site on the FRB domain on the left. On the right, the location and conformation of rapamycin bound to the FRB domain in the ternary complex formed with FKBP12 is illustrated, with the domain shown in the same orientation as on the left.]]

Sandbox Reserved 825: Difference between revisions

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@@ Line 44: / Line 44: @@
 group of phosphatidic acid.
-[[Image:FRB Phosphatidic Acid.png|upright=1.25|left|thumb| Fig.2 A representative view of phosphatidic acid docked into its binding site on the FRB domain.]]
+[[Image:FRB Phosphatidic Acid.png|upright=1.25|center|thumb| Fig.2 A representative view of phosphatidic acid docked into its binding site on the FRB domain.]]
 {{clear}}
 Other molecules like the novel class inhibitor '''HTS-1''' (4-[6-{[(1S,2R)-2-(benzyloxy)cyclopentyl]acety}-4-(2-thienyl)pyridin-2-yl]-4-xobutanoic acid)
@@ Line 51: / Line 51: @@
 binding. <ref> PMID: 17684489  </ref>
-[[Image:FRB HTS-1 Rapamycin.png|left|upright=2| thumb| Fig.3 A representative view of the mTOR inhibitor HTS-1 docked into its binding site on the FRB domain on the left. On the right, the location and conformation of rapamycin bound to the FRB domain in the ternary complex formed with FKBP12 is illustrated, with the domain shown in the same orientation as on the left.]]
+[[Image:FRB HTS-1 Rapamycin.png|center|upright=2| thumb| Fig.3 A representative view of the mTOR inhibitor HTS-1 docked into its binding site on the FRB domain on the left. On the right, the location and conformation of rapamycin bound to the FRB domain in the ternary complex formed with FKBP12 is illustrated, with the domain shown in the same orientation as on the left.]]