Sandbox Reserved 824: Difference between revisions
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==Fonction== | ==Fonction== | ||
''' | *'''Signal peptide binding''' | ||
The signal peptide binds SRP54M in an <scene name='56/568022/Hsrp54m_groove/1'>hydrophobic groove</scene> formed by helices 2, 3 and 4 as well as the loop 349-365 (17 aminoacids) previously mentioned. | The signal peptide binds SRP54M in an <scene name='56/568022/Hsrp54m_groove/1'>hydrophobic groove</scene> formed by helices 2, 3 and 4 as well as the loop 349-365 (17 aminoacids) previously mentioned. | ||
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This hypothesis has however to be confirmed since 1QB2 is only a fragment of SRP54, and that the M-domain, linked to the N and G domains, might adopt another conformation. | This hypothesis has however to be confirmed since 1QB2 is only a fragment of SRP54, and that the M-domain, linked to the N and G domains, might adopt another conformation. | ||
''' | *'''SRP RNA binding''' | ||
SRP54M binds the SRP RNA 7S by electrostatic interactions | SRP54M binds the SRP RNA 7S by electrostatic interactions | ||
