Sandbox Reserved 819: Difference between revisions
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The rhodopsin belongs to the CATH Superfamily 1.20.1070.10.[http://www.cathdb.info/version/3.5.0/superfamily/1.20.1070.10]The protein <scene name='56/568017/Rhodopsin/1'>rhodopsin</scene> has 7 transmembrane alpha helices, embedded in the plasma membrane. These helices are connected to each other by protein loops. | The rhodopsin belongs to the CATH Superfamily 1.20.1070.10.[http://www.cathdb.info/version/3.5.0/superfamily/1.20.1070.10]The protein <scene name='56/568017/Rhodopsin/1'>rhodopsin</scene> has 7 transmembrane alpha helices, embedded in the plasma membrane. These helices are connected to each other by protein loops. | ||
The rhodopsin harvests energy from light to carry out metabolic processes using a non-chlorophyll-based pathway. Thanks to the retinal, the light induces a phototactic response by interacting with transducer membrane-embedded proteins that have no relation to G proteins. There are four different | The rhodopsin harvests energy from light to carry out metabolic processes using a non-chlorophyll-based pathway. Thanks to the retinal, the light induces a phototactic response by interacting with transducer membrane-embedded proteins that have no relation to G proteins. There are four different rhodopsin chains with different structures: A, B, D, E. | ||
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The 2,3-di-phytanyl-glycerol [http://www.ebi.ac.uk/pdbe-srv/pdbechem/chemicalCompound/show/L2P] (C43 H88 O3) is an archaeol (di-O-phytanylglycerol). This is a double ether of sn-1-glycerol where positions 2 and 3 are bound to phytanyl residues. The archaeols are Archaea homologs of diacylglycerols (DAGs). | The 2,3-di-phytanyl-glycerol [http://www.ebi.ac.uk/pdbe-srv/pdbechem/chemicalCompound/show/L2P] (C43 H88 O3) is an archaeol (di-O-phytanylglycerol). This is a double ether of sn-1-glycerol where positions 2 and 3 are bound to phytanyl residues. The archaeols are Archaea homologs of diacylglycerols (DAGs). | ||
It interacts with the aR2 surface and the carbohydrate <scene name='56/568017/Glc/1'>GLC</scene>. It binds to: the A chain thanks to a covalent bond with the carbohydrate alpha-D-glucose 281 (GLC) and thanks to a hydrogen bond with the <scene name='56/568017/Tyr_85/1'>Tyrosine 85</scene>; the B chain thanks to a covalent bond with the carbohydrate alpha-D-glucose 281 (GLC) and thanks to a hydrogen bond with the Tyrosine 85; the D chain thanks to a covalent bond with the carbohydrate alpha-D-glucose 281 (GLC) and thanks to a hydrogen bond with the Tyrosine 85; the E chain thanks to a covalent bond with the carbohydrate alpha-D-glucose 284 (GLC) and thanks to a hydrogen bond with the Tyrosine 85. Others bonds exist like van-der-waals bonds [http://www.ebi.ac.uk/pdbe-site/pdbemotif/?tab=boundmolecule&pdb=2z55&ligandCode3letter=L2P]. | It interacts with the aR2 surface and the carbohydrate <scene name='56/568017/Glc/1'>GLC</scene>. It binds to: the A chain thanks to a covalent bond with the carbohydrate alpha-D-glucose 281 (GLC) and thanks to a hydrogen bond with the <scene name='56/568017/Tyr_85/1'>Tyrosine 85</scene>; the B chain thanks to a covalent bond with the carbohydrate alpha-D-glucose 281 (GLC) and thanks to a hydrogen bond with the Tyrosine 85; the D chain thanks to a covalent bond with the carbohydrate alpha-D-glucose 281 (GLC) and thanks to a hydrogen bond with the Tyrosine 85; the E chain thanks to a covalent bond with the carbohydrate alpha-D-glucose 284 (GLC) and thanks to a hydrogen bond with the Tyrosine 85. Others bonds exist like van-der-waals bonds [http://www.ebi.ac.uk/pdbe-site/pdbemotif/?tab=boundmolecule&pdb=2z55&ligandCode3letter=L2P].<ref name="multiple">PMID:18082767</ref> | ||
