Sandbox Reserved 821: Difference between revisions
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Léa Chuzel (talk | contribs) No edit summary |
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<Structure load='1b09' size='500' frame='true' align='left' caption='Insert caption here' scene='Insert optional scene name here' /> | <Structure load='1b09' size='500' frame='true' align='left' caption='Insert caption here' scene='Insert optional scene name here' /> | ||
Phosphocholine is an universal phospholipid found particularly in the cell membranes and plasma lipoproteins of bacteria, fungi, plants and other eukaryotic organisms whose us, the human beings. However, CRP can only bind phosphocholine of our damaged or apoptotic cells, as head groups of phosphocholine are inaccessible to CRP in “normal” cells. | Phosphocholine is an universal phospholipid found particularly in the cell membranes and plasma lipoproteins of bacteria, fungi, plants and other eukaryotic organisms whose us, the human beings. However, CRP can only bind phosphocholine of our damaged or apoptotic cells, as head groups of phosphocholine are inaccessible to CRP in “normal” cells. | ||
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The role of CRP to protect the host of infection and inflammation is thus certainly done first by binding to phosphocholine or other ligands such as phosphoethanolamine, and then by activation of the classical complement pathway via interaction with C1q or phagocytosis via interaction with Fc receptors. | The role of CRP to protect the host of infection and inflammation is thus certainly done first by binding to phosphocholine or other ligands such as phosphoethanolamine, and then by activation of the classical complement pathway via interaction with C1q or phagocytosis via interaction with Fc receptors. | ||
