Sandbox Reserved 816: Difference between revisions

, which is a Gram-positive bacterium human pathogen.  Its ability to survive in the human intestine and to cross a variety of membranes, including mucosal, intestinal, placental, and blood–brain barriers, allows it to generate illnesses ranging from gastroenteritis in healthy individuals to bacteremia and meningitis in immunocompromised patients, as well as mother-to-child infections. [http://en.wikipedia.org/wiki/Listeria_monocytogenes  Listeria monocytogene] can survive in a variety of cell types and proteins of the internalin family have been shown to play a key role in this survival.

'''The three-dimensional strsuctures of internalin protein''' have revealed a common N-terminal with leucine-rich repeats (LRRs). Their C-terminal is distinct and implies the specific role of the internalin. Among those proteins, '''Internalin K''', outcome of gene lmo1290 in [http://en.wikipedia.org/wiki/Listeria_monocytogenes  Listeria monocytogene], is a surface-associated molecule that can interact with [http://en.wikipedia.org/wiki/Major_vault_protein major vault protein], a cytoplasmic rubonucleoprotein particle.