4mhg: Difference between revisions
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{{STRUCTURE_4mhg| PDB=4mhg | SCENE= }} | |||
===Crystal structure of ETV6 bound to a specific DNA sequence=== | |||
{{ABSTRACT_PUBMED_24333486}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ETV6_MOUSE ETV6_MOUSE]] Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. | |||
==About this Structure== | |||
[[4mhg]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MHG OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024333486</ref><references group="xtra"/><references/> | |||
[[Category: Chan, A C.]] | |||
[[Category: De, S.]] | |||
[[Category: Graves, B J.]] | |||
[[Category: III, H J.Coyne.]] | |||
[[Category: McIntosh, L P.]] | |||
[[Category: Murphy, M E.]] | |||
[[Category: Okon, M.]] | |||
[[Category: Ets domain]] | |||
[[Category: Transcription factor]] | |||
[[Category: Transcription-dna complex]] | |||
Revision as of 10:04, 8 January 2014
Crystal structure of ETV6 bound to a specific DNA sequence
Template:ABSTRACT PUBMED 24333486
Function
[ETV6_MOUSE] Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'.
About this Structure
4mhg is a 3 chain structure. Full crystallographic information is available from OCA.
Reference
- De S, Chan AC, Coyne HJ 3rd, Bhachech N, Hermsdorf U, Okon M, Murphy ME, Graves BJ, McIntosh LP. Steric mechanism of auto-inhibitory regulation of specific and non-specific DNA binding by the ETS transcriptional repressor ETV6. J Mol Biol. 2013 Dec 11. pii: S0022-2836(13)00747-X. doi:, 10.1016/j.jmb.2013.11.031. PMID:24333486 doi:https://dx.doi.org/10.1016/j.jmb.2013.11.031