Sandbox Reserved 818: Difference between revisions
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==Toxin entry and trafficking in target cells== | ==Toxin entry and trafficking in target cells== | ||
After binding to the target cell receptors, PTX enters the cells via receptor mediated endocytosis, and then follows the ''retrograde transport system'', involving both the Golgi apparatus and the endoplasmic reticulum | After binding to the target cell receptors, PTX enters the cells via receptor mediated endocytosis, and then follows the ''retrograde transport system'', involving both the Golgi apparatus and the endoplasmic reticulum | ||
<ref name="Schmidt MA (1997)"> | <ref name="Schmidt MA (1997)"> | ||
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==Structural Informations allow to produce efficient vaccine== | ==Structural Informations allow to produce efficient vaccine== | ||
Cristal structure provided insight into the pathogenic mechanisms of PTX. Informations about the tertiary structure of the active site a good basis for elimination of the catalytic activity in recombinant molecules for vaccine use. | Cristal structure provided insight into the pathogenic mechanisms of PTX. Informations about the tertiary structure of the active site a good basis for elimination of the catalytic activity in recombinant molecules for vaccine use. | ||
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==Reference== | ==Reference== | ||
<references/> | <references/> | ||
==Proteopedia Page Contributors and Editors== | ==Proteopedia Page Contributors and Editors== | ||
