2m9v: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_2m9v| PDB=2m9v | SCENE= }} | {{STRUCTURE_2m9v| PDB=2m9v | SCENE= }} | ||
===Structure of Saccharomyces cerevisiae Est3 protein=== | ===Structure of Saccharomyces cerevisiae Est3 protein=== | ||
{{ABSTRACT_PUBMED_24344315}} | |||
==Function== | ==Function== | ||
| Line 9: | Line 10: | ||
==Reference== | ==Reference== | ||
<references group="xtra"/><references/> | <ref group="xtra">PMID:024344315</ref><references group="xtra"/><references/> | ||
[[Category: Armstrong, G S.]] | [[Category: Armstrong, G S.]] | ||
[[Category: Rao, T.]] | [[Category: Rao, T.]] | ||
[[Category: Wuttke, D S.]] | [[Category: Wuttke, D S.]] | ||
[[Category: Protein binding]] | [[Category: Protein binding]] | ||
Revision as of 07:14, 15 January 2014
Structure of Saccharomyces cerevisiae Est3 protein
Template:ABSTRACT PUBMED 24344315
Function
[EST3_YEAST] Component of the telomerase complex involved in telomere replication. Stimulates RNA/DNA heteroduplex unwinding which favors the telomere replication by the telomerase.[1] [2] [3] [4] [5] [6]
About this Structure
2m9v is a 1 chain structure. Full experimental information is available from OCA.
Reference
- Rao T, Lubin JW, Armstrong GS, Tucey TM, Lundblad V, Wuttke DS. Structure of Est3 reveals a bimodal surface with differential roles in telomere replication. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):214-8. doi: 10.1073/pnas.1316453111. , Epub 2013 Dec 16. PMID:24344315 doi:https://dx.doi.org/10.1073/pnas.1316453111
- ↑ Lendvay TS, Morris DK, Sah J, Balasubramanian B, Lundblad V. Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes. Genetics. 1996 Dec;144(4):1399-412. PMID:8978029
- ↑ Morris DK, Lundblad V. Programmed translational frameshifting in a gene required for yeast telomere replication. Curr Biol. 1997 Dec 1;7(12):969-76. PMID:9382847
- ↑ Lingner J, Cech TR, Hughes TR, Lundblad V. Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity. Proc Natl Acad Sci U S A. 1997 Oct 14;94(21):11190-5. PMID:9326584
- ↑ Diede SJ, Gottschling DE. Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta. Cell. 1999 Dec 23;99(7):723-33. PMID:10619426
- ↑ Sharanov YS, Zvereva MI, Dontsova OA. Saccharomyces cerevisiae telomerase subunit Est3p binds DNA and RNA and stimulates unwinding of RNA/DNA heteroduplexes. FEBS Lett. 2006 Aug 21;580(19):4683-90. Epub 2006 Jul 24. PMID:16884717 doi:https://dx.doi.org/10.1016/j.febslet.2006.07.048
- ↑ Yang CP, Chen YB, Meng FL, Zhou JQ. Saccharomyces cerevisiae Est3p dimerizes in vitro and dimerization contributes to efficient telomere replication in vivo. Nucleic Acids Res. 2006 Jan 17;34(2):407-16. Print 2006. PMID:16418502 doi:https://dx.doi.org/10.1093/nar/gkj445
