4dwq: Difference between revisions
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{{STRUCTURE_4dwq| PDB=4dwq | SCENE= }} | {{STRUCTURE_4dwq| PDB=4dwq | SCENE= }} | ||
===RNA ligase RtcB-GMP/Mn(2+) complex=== | |||
{{ABSTRACT_PUBMED_22949672}} | |||
=== | ==Function== | ||
[[http://www.uniprot.org/uniprot/RTCB_PYRHO RTCB_PYRHO]] tRNA-splicing ligase that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as a RNA ligase with broad substrate specificity, and may function toward other RNAs (By similarity). | |||
==About this Structure== | |||
[[4dwq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/'pyrococcus_shinkaii' 'pyrococcus shinkaii']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DWQ OCA]. | |||
== | ==Reference== | ||
<ref group="xtra">PMID:022949672</ref><references group="xtra"/><references/> | |||
[[Category: Pyrococcus | [[Category: Pyrococcus shinkaii]] | ||
[[Category: Englert, M.]] | [[Category: Englert, M.]] | ||
[[Category: Okada, C.]] | [[Category: Okada, C.]] | ||
Revision as of 07:15, 15 January 2014
RNA ligase RtcB-GMP/Mn(2+) complex
Template:ABSTRACT PUBMED 22949672
Function
[RTCB_PYRHO] tRNA-splicing ligase that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as a RNA ligase with broad substrate specificity, and may function toward other RNAs (By similarity).
About this Structure
4dwq is a 2 chain structure with sequence from 'pyrococcus shinkaii'. Full crystallographic information is available from OCA.
Reference
- Englert M, Xia S, Okada C, Nakamura A, Tanavde V, Yao M, Eom SH, Konigsberg WH, Soll D, Wang J. Structural and mechanistic insights into guanylylation of RNA-splicing ligase RtcB joining RNA between 3'-terminal phosphate and 5'-OH. Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15235-40. Epub 2012 Sep 4. PMID:22949672 doi:https://dx.doi.org/10.1073/pnas.1213795109
