4lyw: Difference between revisions

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4lyw|  PDB=4lyw  |  SCENE=  }}
+===Crystal Structure of BRD4(1) bound to inhibitor XD14===
+{{ABSTRACT_PUBMED_24272870}}
-The entry 4lyw is ON HOLD
+==Disease==
+[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
-Authors: Wohlwend, D., Gerhardt, S., Einsle, O.
+==Function==
+[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
-Description: Crystal Structure of BRD4(1) bound to inhibitor XD14
+==About this Structure==
+[[4lyw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LYW OCA].
+==Reference==
+<ref group="xtra">PMID:024272870</ref><references group="xtra"/><references/>
+[[Category: Einsle, O.]]
+[[Category: Gerhardt, S.]]
+[[Category: Wohlwend, D.]]
+[[Category: Acetylated lysine]]
+[[Category: Brd4 inhibitor]]
+[[Category: Bromodomain]]
+[[Category: Epigenetic reader protein]]
+[[Category: Histone tail]]
+[[Category: Protein binding-inhibitor complex]]

Navigation menu