4irv: Difference between revisions

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~~'''Unreleased structure'''~~

===Structure of the Helicobacter pylori CagA Oncogene Bound to the Human Tumor Suppressor Apoptosis-stimulating Protein of p53-2===

~~The entry 4irv~~ is ~~ON HOLD~~ ~~until Mar 12 2015~~

==Function==

[[http://www.uniprot.org/uniprot/CAGA_HELPY CAGA_HELPY]] May be necessary for the transcription, folding, export, or function of the cytotoxin. [[http://www.uniprot.org/uniprot/ASPP2_HUMAN ASPP2_HUMAN]] Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.<ref>PMID:11684014</ref> <ref>PMID:12694406</ref> <ref>PMID:19377511</ref>

~~Authors~~: ~~Stebbins, C~~.E.~~, Nesic, D~~.

==About this Structure==

[[4irv]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IRV OCA].

~~Description~~: ~~Structure of the Helicobacter pylori CagA Oncogene Bound to the Human Tumor Suppressor Apoptosis-stimulating~~ Protein ~~of p53-2~~

==Reference==

[[Category: Nesic, D.]]

[[Category: Stebbins, C E.]]

[[Category: Protein binding]]

[[Category: Virulence factor and tumor suppressor]]

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-'''Unreleased structure'''
+{{STRUCTURE_4irv|  PDB=4irv  |  SCENE=  }}
+===Structure of the Helicobacter pylori CagA Oncogene Bound to the Human Tumor Suppressor Apoptosis-stimulating Protein of p53-2===
-The entry 4irv is ON HOLD  until Mar 12 2015
+==Function==
+[[http://www.uniprot.org/uniprot/CAGA_HELPY CAGA_HELPY]] May be necessary for the transcription, folding, export, or function of the cytotoxin. [[http://www.uniprot.org/uniprot/ASPP2_HUMAN ASPP2_HUMAN]] Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.<ref>PMID:11684014</ref> <ref>PMID:12694406</ref> <ref>PMID:19377511</ref>
-Authors: Stebbins, C.E., Nesic, D.
+==About this Structure==
+[[4irv]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IRV OCA].
-Description: Structure of the Helicobacter pylori CagA Oncogene Bound to the Human Tumor Suppressor Apoptosis-stimulating Protein of p53-2
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Nesic, D.]]
+[[Category: Stebbins, C E.]]
+[[Category: Protein binding]]
+[[Category: Virulence factor and tumor suppressor]]