4o2w: Difference between revisions

Line 1:

~~'''Unreleased~~ structure~~'''~~

===Crystal structure of the third RCC1-like domain of HERC1===

~~The entry 4o2w~~ is ~~ON HOLD~~

==Function==

[[http://www.uniprot.org/uniprot/HERC1_HUMAN HERC1_HUMAN]] Involved in membrane trafficking via some guanine nucleotide exchange factor (GEF) activity and its ability to bind clathrin. Acts as a GEF for Arf and Rab, by exchanging bound GDP for free GTP. Binds phosphatidylinositol 4,5-bisphosphate, which is required for GEF activity. May also act as a E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.<ref>PMID:8861955</ref> <ref>PMID:9233772</ref> <ref>PMID:15642342</ref>

~~Authors~~: ~~Dong, A., Hu, J., Li, Y., Walker, J.R., Bountra, C., Arrowsmith, C.H~~.~~, Edwards, A~~.M.~~, Tong, Y~~.~~, Structural Genomics Consortium (SGC)~~

==About this Structure==

[[4o2w]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O2W OCA].

~~Description~~: ~~Crystal structure of the third RCC1~~-~~like domain of HERC1~~

==Reference==

[[Category: Arrowsmith, C H.]]

[[Category: Bountra, C.]]

[[Category: Dong, A.]]

[[Category: Edwards, A M.]]

[[Category: Hu, J.]]

[[Category: Li, Y.]]

[[Category: SGC, Structural Genomics Consortium.]]

[[Category: Tong, Y.]]

[[Category: Walker, J R.]]

[[Category: Beta-propeller]]

[[Category: Herc1]]

[[Category: Ligase]]

[[Category: Rcc1]]

[[Category: Rld]]

[[Category: Sgc]]

[[Category: Structural genomic]]

[[Category: Structural genomics consortium]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4o2w|  PDB=4o2w  |  SCENE=  }}
+===Crystal structure of the third RCC1-like domain of HERC1===
-The entry 4o2w is ON HOLD
+==Function==
+[[http://www.uniprot.org/uniprot/HERC1_HUMAN HERC1_HUMAN]] Involved in membrane trafficking via some guanine nucleotide exchange factor (GEF) activity and its ability to bind clathrin. Acts as a GEF for Arf and Rab, by exchanging bound GDP for free GTP. Binds phosphatidylinositol 4,5-bisphosphate, which is required for GEF activity. May also act as a E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.<ref>PMID:8861955</ref> <ref>PMID:9233772</ref> <ref>PMID:15642342</ref>
-Authors: Dong, A., Hu, J., Li, Y., Walker, J.R., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Tong, Y., Structural Genomics Consortium (SGC)
+==About this Structure==
+[[4o2w]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O2W OCA].
-Description: Crystal structure of the third RCC1-like domain of HERC1
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Arrowsmith, C H.]]
+[[Category: Bountra, C.]]
+[[Category: Dong, A.]]
+[[Category: Edwards, A M.]]
+[[Category: Hu, J.]]
+[[Category: Li, Y.]]
+[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Tong, Y.]]
+[[Category: Walker, J R.]]
+[[Category: Beta-propeller]]
+[[Category: Herc1]]
+[[Category: Ligase]]
+[[Category: Rcc1]]
+[[Category: Rld]]
+[[Category: Sgc]]
+[[Category: Structural genomic]]
+[[Category: Structural genomics consortium]]