1gtw: Difference between revisions

Line 1:

~~[[Image:1gtw.png|left|200px]]~~

===crystal structure of C/EBPbeta bZip homodimer bound to a DNA fragment from the tom-1A promoter===

===~~CRYSTAL STRUCTURE OF C~~/~~EBPBETA BZIP DIMERIC BOUND TO A DNA FRAGMENT FROM THE TOM~~-~~1A PROMOTER===~~

==Function==

[[http://www.uniprot.org/uniprot/CEBPB_HUMAN CEBPB_HUMAN]] Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses. Specifically binds to an IL-1 response element in the IL-6 gene. NF-IL6 also binds to regulatory regions of several acute-phase and cytokines genes. It probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Functions in brown adipose tissue (BAT) differentiation (By similarity). Regulates the transcriptional induction of peroxisome proliferator-activated receptor gamma (PPARG).<ref>PMID:20829347</ref>

~~{{ABSTRACT_PUBMED_11792321}}~~

==About this Structure==

[[1gtw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GTW OCA].

[[1gtw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GTW OCA].

==Reference==

[[Category: ~~Homo sapiens~~]]

[[Category: Human]]

[[Category: Ogata, K.]]

[[Category: Tahirov, T H.]]

~~[[Category: Bzip]]~~

[[Category: C/ebp]]

[[Category: ~~Htpothetical~~ protein]]

[[Category: Hypothetical protein]]

[[Category: Protein-dna complex]]

[[Category: Transcription factor]]

[[Category: Transcription-dna complex]]

[[Category: Transcription/dna]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-[[Image:1gtw.png|left|200px]]
 {{STRUCTURE_1gtw|  PDB=1gtw  |  SCENE=  }}
+===crystal structure of C/EBPbeta bZip homodimer bound to a DNA fragment from the tom-1A promoter===
+{{ABSTRACT_PUBMED_11792321}}
-===CRYSTAL STRUCTURE OF C/EBPBETA BZIP DIMERIC BOUND TO A DNA FRAGMENT FROM THE TOM-1A PROMOTER===
+==Function==
+[[http://www.uniprot.org/uniprot/CEBPB_HUMAN CEBPB_HUMAN]] Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses. Specifically binds to an IL-1 response element in the IL-6 gene. NF-IL6 also binds to regulatory regions of several acute-phase and cytokines genes. It probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Functions in brown adipose tissue (BAT) differentiation (By similarity). Regulates the transcriptional induction of peroxisome proliferator-activated receptor gamma (PPARG).<ref>PMID:20829347</ref>
-{{ABSTRACT_PUBMED_11792321}}
 ==About this Structure==
-[[1gtw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GTW OCA].
+[[1gtw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GTW OCA].
 ==Reference==
-<ref group="xtra">PMID:011792321</ref><references group="xtra"/>
+<ref group="xtra">PMID:011792321</ref><references group="xtra"/><references/>
-[[Category: Homo sapiens]]
+[[Category: Human]]
 [[Category: Ogata, K.]]
 [[Category: Tahirov, T H.]]
-[[Category: Bzip]]
 [[Category: C/ebp]]
-[[Category: Htpothetical protein]]
+[[Category: Hypothetical protein]]
 [[Category: Protein-dna complex]]
 [[Category: Transcription factor]]
 [[Category: Transcription-dna complex]]
 [[Category: Transcription/dna]]