3k92: Difference between revisions
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{{STRUCTURE_3k92| PDB=3k92 | SCENE= }} | {{STRUCTURE_3k92| PDB=3k92 | SCENE= }} | ||
===Crystal structure of a E93K mutant of the majour Bacillus subtilis glutamate dehydrogenase RocG=== | ===Crystal structure of a E93K mutant of the majour Bacillus subtilis glutamate dehydrogenase RocG=== | ||
{{ABSTRACT_PUBMED_20630473}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DHE2_BACSU DHE2_BACSU]] Devoted to catabolic function of glutamate (and other amino acids of the glutamate family) utilization as sole nitrogen source. It is not involved in anabolic function of glutamate biosynthesis since B.subtilis possesses only one route of glutamate biosynthesis from ammonia, catalyzed by glutamate synthase. RocG is unable to utilize glutamate or glutamine as sole carbon source and to synthesize glutamate, but it is involved in the utilization of arginine, and proline as carbon or nitrogen source. The catabolic RocG is essential for controlling gltAB expression via an inhibitory interactions with the transcriptional regulator GltC in response to the availability of sugars.<ref>PMID:9829940</ref> <ref>PMID:17183217</ref> <ref>PMID:18326565</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3k92]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3k92]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K92 OCA]. | ||
==See Also== | ==See Also== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:020630473</ref><references group="xtra"/> | <ref group="xtra">PMID:020630473</ref><references group="xtra"/><references/> | ||
[[Category: Bacillus | [[Category: Bacillus globigii migula 1900]] | ||
[[Category: Glutamate dehydrogenase]] | [[Category: Glutamate dehydrogenase]] | ||
[[Category: Commichau, F M.]] | [[Category: Commichau, F M.]] | ||
