4lbk: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4lbk|  PDB=4lbk  |  SCENE=  }}
===Crystal structure of Human galectin-3 CRD K176L mutant in complex with LNnT===
{{ABSTRACT_PUBMED_24326249}}


The entry 4lbk is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/LEG3_HUMAN LEG3_HUMAN]] Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.<ref>PMID:15181153</ref> <ref>PMID:19594635</ref> <ref>PMID:19616076</ref>  


Authors: Bum-Erdene, K., Blanchard, H.
==About this Structure==
[[4lbk]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LBK OCA].  


Description: Crystal structure of Human galectin-3 CRD K176L mutant in complex with LNnT
==Reference==
<ref group="xtra">PMID:024326249</ref><references group="xtra"/><references/>
[[Category: Blanchard, H.]]
[[Category: Bum-Erdene, K.]]
[[Category: Beta sandwich]]
[[Category: Carbohydrate binding protein]]
[[Category: Carbohydrate-recognition]]
[[Category: Galectin]]
[[Category: Glycosphingolipid]]
[[Category: Lnnt]]
[[Category: Sugar binding protein]]
Retrieved from "https://proteopedia.org/4lbk"