3w44: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_3w44|  PDB=3w44  |  SCENE=  }}
===Crystal structure of RsbX, selenomethionine derivative===


The entry 3w44 is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/RSBX_BACSU RSBX_BACSU]] Negative regulator of sigma-B activity. Dephosphorylates RsbS. Plays a role both in maintaining low sigma-B activity during growth and in reestablishing prestress sigma-B activity after induction. Could have a negative feedback role by indirectly communicating sigma-B protein levels.<ref>PMID:1592822</ref> <ref>PMID:8468294</ref> <ref>PMID:8824586</ref> <ref>PMID:9658013</ref>  


Authors: Teh, A.H., Makino, M., Baba, S., Shimizu, N., Yamamoto, M., Kumasaka, T.
==About this Structure==
[[3w44]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W44 OCA].  


Description: Crystal structure of RsbX, selenomethionine derivative
==Reference==
<references group="xtra"/><references/>
[[Category: Phosphoserine phosphatase]]
[[Category: Baba, S.]]
[[Category: Kumasaka, T.]]
[[Category: Makino, M.]]
[[Category: Shimizu, N.]]
[[Category: Teh, A H.]]
[[Category: Yamamoto, M.]]
[[Category: Dephosphorylation]]
[[Category: Environmental stress]]
[[Category: Gene expression regulation]]
[[Category: Hydrolase]]
[[Category: Hydrolase protein phosphatase]]
[[Category: Magnesium/manganese binding]]
[[Category: Phosphatase]]
[[Category: Phosphoric monoester hydrolase]]
[[Category: Protein structure]]
[[Category: Signaling protein]]
[[Category: Stressosome]]
[[Category: Tertiary]]

Revision as of 07:00, 22 January 2014

Template:STRUCTURE 3w44

Crystal structure of RsbX, selenomethionine derivative

Function

[RSBX_BACSU] Negative regulator of sigma-B activity. Dephosphorylates RsbS. Plays a role both in maintaining low sigma-B activity during growth and in reestablishing prestress sigma-B activity after induction. Could have a negative feedback role by indirectly communicating sigma-B protein levels.[1] [2] [3] [4]

About this Structure

3w44 is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  1. ↑ Boylan SA, Rutherford A, Thomas SM, Price CW. Activation of Bacillus subtilis transcription factor sigma B by a regulatory pathway responsive to stationary-phase signals. J Bacteriol. 1992 Jun;174(11):3695-706. PMID:1592822
  2. ↑ Benson AK, Haldenwang WG. Regulation of sigma B levels and activity in Bacillus subtilis. J Bacteriol. 1993 Apr;175(8):2347-56. PMID:8468294
  3. ↑ Yang X, Kang CM, Brody MS, Price CW. Opposing pairs of serine protein kinases and phosphatases transmit signals of environmental stress to activate a bacterial transcription factor. Genes Dev. 1996 Sep 15;10(18):2265-75. PMID:8824586
  4. ↑ Smirnova N, Scott J, Voelker U, Haldenwang WG. Isolation and characterization of Bacillus subtilis sigB operon mutations that suppress the loss of the negative regulator RsbX. J Bacteriol. 1998 Jul;180(14):3671-80. PMID:9658013

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