3zif: Difference between revisions
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{{STRUCTURE_3zif| PDB=3zif | SCENE= }} | |||
===Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CAPSH_ADEB3 CAPSH_ADEB3]] Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid. Assembled into trimeric units with the help of the chaperone shutoff protein. Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid. Might be involved, through its interaction with host dyneins, in the intracellular microtubule-dependent transport of incoming viral capsid to the nucleus (By similarity). | |||
==About this Structure== | |||
[[3zif]] is a 18 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovine_adenovirus_3 Bovine adenovirus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZIF OCA]. | |||
[[Category: Bovine adenovirus 3]] | |||
[[Category: Cheng, L.]] | |||
[[Category: Huang, X.]] | |||
[[Category: Ji, G.]] | |||
[[Category: Li, X.]] | |||
[[Category: Liu, H.]] | |||
[[Category: Sun, F.]] | |||
[[Category: Sun, W.]] | |||
[[Category: Wang, Y.]] | |||
[[Category: Xiong, W.]] | |||
[[Category: Yang, C.]] | |||
[[Category: Zhang, K.]] | |||
[[Category: Zheng, C.]] | |||
[[Category: Zhu, P.]] | |||
[[Category: Assembly intermediate]] | |||
[[Category: Virus]] | |||
Revision as of 07:00, 22 January 2014
Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly
Function
[CAPSH_ADEB3] Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid. Assembled into trimeric units with the help of the chaperone shutoff protein. Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid. Might be involved, through its interaction with host dyneins, in the intracellular microtubule-dependent transport of incoming viral capsid to the nucleus (By similarity).
About this Structure
3zif is a 18 chain structure with sequence from Bovine adenovirus 3. Full crystallographic information is available from OCA.