4o8y: Difference between revisions
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{{STRUCTURE_4o8y| PDB=4o8y | SCENE= }} | |||
===Zinc-free Rpn11 in complex with Rpn8=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RPN8_YEAST RPN8_YEAST]] Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.<ref>PMID:9584156</ref> [[http://www.uniprot.org/uniprot/RPN11_YEAST RPN11_YEAST]] Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.<ref>PMID:21075847</ref> | |||
==About this Structure== | |||
[[4o8y]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O8Y OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Martin, A.]] | |||
[[Category: Padovani, C.]] | |||
[[Category: Worden, E J.]] | |||
[[Category: Deubiquitinase]] | |||
[[Category: Hydrolase]] | |||
[[Category: Mpn jamm]] | |||
Revision as of 07:06, 22 January 2014
Zinc-free Rpn11 in complex with Rpn8
Function
[RPN8_YEAST] Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.[1] [RPN11_YEAST] Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.[2]
About this Structure
4o8y is a 2 chain structure. Full crystallographic information is available from OCA.
Reference
- ↑ Glickman MH, Rubin DM, Fried VA, Finley D. The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol. 1998 Jun;18(6):3149-62. PMID:9584156
- ↑ Chen L, Romero L, Chuang SM, Tournier V, Joshi KK, Lee JA, Kovvali G, Madura K. Sts1 plays a key role in targeting proteasomes to the nucleus. J Biol Chem. 2011 Jan 28;286(4):3104-18. doi: 10.1074/jbc.M110.135863. Epub 2010 , Nov 12. PMID:21075847 doi:10.1074/jbc.M110.135863
