3ai8: Difference between revisions
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{{STRUCTURE_3ai8| PDB=3ai8 | SCENE= }} | {{STRUCTURE_3ai8| PDB=3ai8 | SCENE= }} | ||
===Cathepsin B in complex with the nitroxoline=== | ===Cathepsin B in complex with the nitroxoline=== | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/CATB_HUMAN CATB_HUMAN]] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. | |||
==About this Structure== | ==About this Structure== | ||
[[3ai8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3ai8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AI8 OCA]. | ||
==See Also== | ==See Also== | ||
| Line 13: | Line 12: | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:021598397</ref><references group="xtra"/> | <ref group="xtra">PMID:021598397</ref><references group="xtra"/><references/> | ||
[[Category: Cathepsin B]] | [[Category: Cathepsin B]] | ||
[[Category: | [[Category: Human]] | ||
[[Category: Gobec, S.]] | [[Category: Gobec, S.]] | ||
[[Category: Kos, J.]] | [[Category: Kos, J.]] | ||
Revision as of 05:38, 29 January 2014
Cathepsin B in complex with the nitroxoline
Function
[CATB_HUMAN] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
About this Structure
3ai8 is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA.
See Also
Reference
- Mirkovic B, Renko M, Turk S, Sosic I, Jevnikar Z, Obermajer N, Turk D, Gobec S, Kos J. Novel Mechanism of Cathepsin B Inhibition by Antibiotic Nitroxoline and Related Compounds. ChemMedChem. 2011 May 20. doi: 10.1002/cmdc.201100098. PMID:21598397 doi:10.1002/cmdc.201100098
