3fsr: Difference between revisions
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===Chimera of alcohol dehydrogenase by exchange of the cofactor binding domain res 153-295 of T. brockii ADH by C. beijerinckii ADH=== | ===Chimera of alcohol dehydrogenase by exchange of the cofactor binding domain res 153-295 of T. brockii ADH by C. beijerinckii ADH=== | ||
{{ABSTRACT_PUBMED_20102159}} | {{ABSTRACT_PUBMED_20102159}} | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/ADH_THEBR ADH_THEBR]] Alcohol dehydrogenase with a preference for medium chain secondary alcohols, such as 2-butanol and isopropanol. Has very low activity with primary alcohols, such as ethanol. Under physiological conditions, the enzyme reduces aldehydes and 2-ketones to produce secondary alcohols. Is also active with acetaldehyde and propionaldehyde. | |||
==About this Structure== | ==About this Structure== | ||
[[3fsr]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3fsr]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"clostridium_rubrum"_ng_and_vaughn_1963 "clostridium rubrum" ng and vaughn 1963]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FSR OCA]. | ||
==See Also== | ==See Also== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:020102159</ref><references group="xtra"/> | <ref group="xtra">PMID:020102159</ref><references group="xtra"/><references/> | ||
[[Category: Clostridium | [[Category: Clostridium rubrum ng and vaughn 1963]] | ||
[[Category: Burstein, Y.]] | [[Category: Burstein, Y.]] | ||
[[Category: Frolow, F.]] | [[Category: Frolow, F.]] | ||
