3w3x: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[3w3x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3w3x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W3X OCA]. | ||
[[Category: | |||
==Reference== | |||
<ref group="xtra">PMID:023541588</ref><references group="xtra"/><references/> | |||
[[Category: Atcc 18824]] | |||
[[Category: Kobayashi, J.]] | [[Category: Kobayashi, J.]] | ||
[[Category: Matsuura, Y.]] | [[Category: Matsuura, Y.]] | ||
Revision as of 05:45, 29 January 2014
Crystal structure of Kap121p bound to Pho4p
Template:ABSTRACT PUBMED 23541588
Function
[IMB3_YEAST] Involved in the nuclear import of ribosomal proteins. Binds to nucleoporins and the GTP-bound form of GSP1 (Ran). Plays a role in protein secretion. [PHO4_YEAST] Transcriptional activator that regulates the expression of repressible phosphatase under phosphate starvation conditions. Binds to the upstream activating sequence (UAS) of several phosphatase encoding PHO genes. Inhibited by the cyclin-CDK PHO80-PHO85 under high-phosphate conditions.
About this Structure
3w3x is a 2 chain structure with sequence from Atcc 18824. Full crystallographic information is available from OCA.
Reference
- Kobayashi J, Matsuura Y. Structural basis for cell-cycle dependent nuclear import mediated by the karyopherin Kap121p. J Mol Biol. 2013 Mar 27. pii: S0022-2836(13)00194-0. doi:, 10.1016/j.jmb.2013.02.035. PMID:23541588 doi:https://dx.doi.org/10.1016/j.jmb.2013.02.035
