2m45: Difference between revisions

Line 1:

~~'''Unreleased~~ structure~~'''~~

===NMR solution structure of the C-terminus of the minichromosome maintenance protein MCM from Sulfolobus solfataricus===

The ~~entry 2m45~~ is ~~ON HOLD~~ ~~until Paper Publication~~

==Function==

[[http://www.uniprot.org/uniprot/MCM_SULSO MCM_SULSO]] Presumptive replicative helicase. Has ATPase and DNA helicase activities. The latter preferentially melts 5'-tailed oligonucleotides and is stimulated by the SSB protein (single-stranded DNA binding protein). The active ATPase sites in the MCM ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The helicase function is proposed to use a partially sequential mode of ATP hydrolysis; the complex appears to tolerate multiple catalytically inactive subunits.<ref>PMID:11821426</ref>

~~Authors~~: ~~Wiedemann, C., Ohlenschlager, O~~.~~, Medagli, B~~.~~, Onesti, S~~.~~, Gorlach, M~~.

==About this Structure==

[[2m45]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M45 OCA].

~~Description~~: ~~NMR solution structure of the~~ C-~~terminus of the minichromosome~~ maintenance protein ~~MCM from Sulfolobus solfataricus~~

==Reference==

[[Category: DNA helicase]]

[[Category: Gorlach, M.]]

[[Category: Medagli, B.]]

[[Category: Ohlenschlager, O.]]

[[Category: Onesti, S.]]

[[Category: Wiedemann, C.]]

[[Category: Dna helicase]]

[[Category: Helix-turn-helix]]

[[Category: Hydrolase]]

[[Category: Mcm]]

[[Category: Minichromosome maintenance protein]]

[[Category: Pre-replicative complex]]

[[Category: Replication]]

[[Category: Thermophile protein]]

[[Category: Winged helix]]

[[Category: Winged helix turn]]

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-'''Unreleased structure'''
+{{STRUCTURE_2m45|  PDB=2m45  |  SCENE=  }}
+===NMR solution structure of the C-terminus of the minichromosome maintenance protein MCM from Sulfolobus solfataricus===
-The entry 2m45 is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/MCM_SULSO MCM_SULSO]] Presumptive replicative helicase. Has ATPase and DNA helicase activities. The latter preferentially melts 5'-tailed oligonucleotides and is stimulated by the SSB protein (single-stranded DNA binding protein). The active ATPase sites in the MCM ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The helicase function is proposed to use a partially sequential mode of ATP hydrolysis; the complex appears to tolerate multiple catalytically inactive subunits.<ref>PMID:11821426</ref>
-Authors: Wiedemann, C., Ohlenschlager, O., Medagli, B., Onesti, S., Gorlach, M.
+==About this Structure==
+[[2m45]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M45 OCA].
-Description: NMR solution structure of the C-terminus of the minichromosome maintenance protein MCM from Sulfolobus solfataricus
+==Reference==
+<references group="xtra"/><references/>
+[[Category: DNA helicase]]
+[[Category: Gorlach, M.]]
+[[Category: Medagli, B.]]
+[[Category: Ohlenschlager, O.]]
+[[Category: Onesti, S.]]
+[[Category: Wiedemann, C.]]
+[[Category: Dna helicase]]
+[[Category: Helix-turn-helix]]
+[[Category: Hydrolase]]
+[[Category: Mcm]]
+[[Category: Minichromosome maintenance protein]]
+[[Category: Pre-replicative complex]]
+[[Category: Replication]]
+[[Category: Thermophile protein]]
+[[Category: Winged helix]]
+[[Category: Winged helix turn]]