3ecs: Difference between revisions
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{{STRUCTURE_3ecs| PDB=3ecs | SCENE= }} | {{STRUCTURE_3ecs| PDB=3ecs | SCENE= }} | ||
===Crystal structure of human eIF2B alpha=== | |||
{{ABSTRACT_PUBMED_19631657}} | |||
== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/EI2BA_HUMAN EI2BA_HUMAN]] Cree leukoencephalopathy;Late infantile CACH syndrome;Ovarioleukodystrophy. The disease is caused by mutations affecting the gene represented in this entry. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/EI2BA_HUMAN EI2BA_HUMAN]] Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. | |||
==About this Structure== | ==About this Structure== | ||
[[3ecs]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3ecs]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ECS OCA]. | ||
==See Also== | ==See Also== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:019631657</ref><references group="xtra"/> | <ref group="xtra">PMID:019631657</ref><references group="xtra"/><references/> | ||
[[Category: | [[Category: Human]] | ||
[[Category: Hiyama, T B.]] | [[Category: Hiyama, T B.]] | ||
[[Category: Ito, T.]] | [[Category: Ito, T.]] | ||
Revision as of 08:00, 5 February 2014
Crystal structure of human eIF2B alpha
Template:ABSTRACT PUBMED 19631657
Disease
[EI2BA_HUMAN] Cree leukoencephalopathy;Late infantile CACH syndrome;Ovarioleukodystrophy. The disease is caused by mutations affecting the gene represented in this entry.
Function
[EI2BA_HUMAN] Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
About this Structure
3ecs is a 8 chain structure with sequence from Human. Full crystallographic information is available from OCA.
See Also
Reference
- Hiyama TB, Ito T, Imataka H, Yokoyama S. Crystal structure of the alpha subunit of human translation initiation factor 2B. J Mol Biol. 2009 Oct 2;392(4):937-51. Epub 2009 Jul 23. PMID:19631657 doi:10.1016/j.jmb.2009.07.054
