2r0k: Difference between revisions

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[[Image:2r0k.png|left|200px]]
{{STRUCTURE_2r0k|  PDB=2r0k  |  SCENE=  }}  
{{STRUCTURE_2r0k|  PDB=2r0k  |  SCENE=  }}  
===Protease domain of HGFA with inhibitor Fab58===
===Protease domain of HGFA with inhibitor Fab58===
{{ABSTRACT_PUBMED_18077410}}


{{ABSTRACT_PUBMED_18077410}}
==Function==
[[http://www.uniprot.org/uniprot/HGFA_HUMAN HGFA_HUMAN]] Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.


==About this Structure==
==About this Structure==
[[2r0k]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R0K OCA].  
[[2r0k]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R0K OCA].  


==See Also==
==See Also==
Line 14: Line 13:


==Reference==
==Reference==
<ref group="xtra">PMID:018077410</ref><references group="xtra"/>
<ref group="xtra">PMID:018077410</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Eigenbrot, C.]]
[[Category: Eigenbrot, C.]]
[[Category: Shia, S.]]
[[Category: Shia, S.]]

Revision as of 08:17, 5 February 2014

Template:STRUCTURE 2r0k

Protease domain of HGFA with inhibitor Fab58

Template:ABSTRACT PUBMED 18077410

Function

[HGFA_HUMAN] Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.

About this Structure

2r0k is a 3 chain structure with sequence from [1] and Human. Full crystallographic information is available from OCA.

See Also

Reference

  1. Wu Y, Eigenbrot C, Liang WC, Stawicki S, Shia S, Fan B, Ganesan R, Lipari MT, Kirchhofer D. Structural insight into distinct mechanisms of protease inhibition by antibodies. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19784-9. Epub 2007 Dec 5. PMID:18077410

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