4cge: Difference between revisions
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{{STRUCTURE_4cge| PDB=4cge | SCENE= }} | |||
===Bacterial secreted hydrolase A=== | |||
{{ABSTRACT_PUBMED_24452911}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RPFE_MYCTU RPFE_MYCTU]] Factor that stimulates resuscitation of dormant cells. Has peptidoglycan (PG) hydrolytic activity. Active in the pM concentration range. Has little to no effect on actively-growing cells. PG fragments could either directly activate the resuscitation pathway of dormant bacteria or serve as a substrate for endogenous Rpf, resulting in low molecular weight products with resuscitation activity.<ref>PMID:12410821</ref> Stimulates growth of stationary phase M.bovis (a slow-growing Mycobacterium), reduces the lag phase of diluted fast-growers M.smegmatis and Micrococcus luteus. Sequential gene disruption indicates RpfB and RpfE are higher than RpfD and RpfC in functional hierarchy.<ref>PMID:12410821</ref> | |||
==About this Structure== | |||
[[4cge]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CGE OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024452911</ref><references group="xtra"/><references/> | |||
[[Category: Alber, T.]] | |||
[[Category: Mavrici, D.]] | |||
[[Category: Prigozhin, D M.]] | |||
[[Category: Hydrolase]] | |||
[[Category: Secreted protein]] | |||