4mr0: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4mr0|  PDB=4mr0  |  SCENE=  }}
===Crystal structure of PfbA, a surface adhesin of Streptococcus pneumoniae===
{{ABSTRACT_PUBMED_24321492}}


The entry 4mr0 is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/PFBA_STRR6 PFBA_STRR6]] Acts as a fibronectin-dependent adhesin and invasin. Binds host (in this case human) fibronectin, plasmin, plasminogen, and human serum albumin. Where the bacteria adhere to human cells there is major recruitment of microvilli which seem to fuse to cover the streptococcal chains. Antibodies to this protein reduce bacterial growth in human blood.


Authors: Ponnuraj, K., Beulin, J.D.S.
==About this Structure==
[[4mr0]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MR0 OCA].  


Description: Crystal structure of PfbA, a surface adhesin of Streptococcus pneumoniae
==Reference==
<ref group="xtra">PMID:024321492</ref><references group="xtra"/><references/>
[[Category: Beulin, D S.J.]]
[[Category: Ponnuraj, K.]]
[[Category: Adhesion]]
[[Category: Cell adhesion]]
[[Category: Fibronectin]]
[[Category: Plasimin and fibronectin-binding protein]]
[[Category: Plasminogen]]
[[Category: Surface protein]]