4bke: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

===Recombinant human serum albumin with palmitic acid. Synthetic cationic antimicrobial peptides bind with their hydrophobic parts to drug site II of human serum albumin===

~~The~~ entry ~~4bke~~ is ~~ON HOLD~~ ~~until Paper Publication~~

==Disease==

[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[http://omim.org/entry/103600 103600]]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>

~~Authors~~: ~~Sivertsen~~, A., ~~Isaksson~~, J., ~~Leiros~~, ~~H.-~~K~~.S.~~, ~~Svenson, J.~~, ~~Svendsen~~, J.-S., ~~Brandsdal, B.-O~~.

==Function==

[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>

~~Description~~: ~~Recombinant human serum albumin with palmitic acid~~. ~~Synthetic cationic antimicrobial peptides bind with their hydrophobic parts to drug site II of human serum albumin~~

==About this Structure==

[[4bke]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BKE OCA].

==Reference==

[[Category: Brandsdal, B O.]]

[[Category: Isaksson, J.]]

[[Category: Leiros, H K.S.]]

[[Category: Sivertsen, A.]]

[[Category: Svendsen, J S.]]

[[Category: Svenson, J.]]

[[Category: Albumin binding]]

[[Category: Group epitope mapping]]

[[Category: Molecular docking]]

[[Category: Transport protein]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4bke|  PDB=4bke  |  SCENE=  }}
+===Recombinant human serum albumin with palmitic acid. Synthetic cationic antimicrobial peptides bind with their hydrophobic parts to drug site II of human serum albumin===
+{{ABSTRACT_PUBMED_24456893}}
-The entry 4bke is ON HOLD  until Paper Publication
+==Disease==
+[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[http://omim.org/entry/103600 103600]]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>
-Authors: Sivertsen, A., Isaksson, J., Leiros, H.-K.S., Svenson, J., Svendsen, J.-S., Brandsdal, B.-O.
+==Function==
+[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>
-Description: Recombinant human serum albumin with palmitic acid. Synthetic cationic antimicrobial peptides bind with their hydrophobic parts to drug site II of human serum albumin
+==About this Structure==
+[[4bke]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BKE OCA].
+==Reference==
+<ref group="xtra">PMID:024456893</ref><references group="xtra"/><references/>
+[[Category: Brandsdal, B O.]]
+[[Category: Isaksson, J.]]
+[[Category: Leiros, H K.S.]]
+[[Category: Sivertsen, A.]]
+[[Category: Svendsen, J S.]]
+[[Category: Svenson, J.]]
+[[Category: Albumin binding]]
+[[Category: Group epitope mapping]]
+[[Category: Molecular docking]]
+[[Category: Transport protein]]